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An image made with a drone shows air handling units on the roof of a CloudHQ data center in Ashburn, Virginia. An image made with a drone shows air handling units on the roof of a CloudHQ data center in Ashburn, Virginia. Mon 8 Dec 2025 07.00 ESTLast modified on Mon 8 Dec 2025 08.41 EST A coalition of more than 230 environmental groups has demanded a national moratorium on new datacenters in the US, the latest salvo in a growing backlash to a booming artificial intelligence industry that has been blamed for escalating electricity bills and worsening the climate crisis. The green groups, including Greenpeace, Friends of the Earth, Food & Water Watch and dozens of local organizations, have urged members of Congress to halt the proliferation of energy-hungry datacenters, accusing them of causing planet-heating emissions, sucking up vast amounts of water and for exacerbating electricity bill increases that have hit Americans this year. The push comes amid a growing revolt against moves by companies such as Meta, Google and Open AI to plow hundreds of billions of dollars into new datacenters, primarily to meet the huge computing demands of AI.

An aerial view of an Amazon Web Services Data Center known as U.S. East 1 in Ashburn, Virginia, on Oct. 20 | REUTERS STOCKHOLM/LONDON - The global boom in data centers as companies increasingly outsource information storage and ramp up use of energy-intensive artificial intelligence is creating a key challenge for the industry -- how to keep cool. An outage at the world's biggest exchange operator CME Group from late Thursday that halted trade on its popular currency platform and in futures spanning foreign exchange, commodities, Treasuries and stocks has put a spotlight on data centers overheating. The problem was a cooling issue at data centers operated by Dallas-headquartered CyrusOne, which operates more than 55 centers in the U.S., Europe and Japan. In a time of both misinformation and too much information, quality journalism is more crucial than ever. By subscribing, you can help us get the story right.

Several large tech firms that are active in AI have set goals to hit net zero by 2030, but a new forecast of the energy and water required to run large data centres shows they're unlikely to meet those targets As the AI industry rapidly expands, questions about the environmental impact of data centres are coming to the forefront - and a new forecast warns the industry is unlikely to meet net zero targets by 2030. Fengqi You at Cornell University in New York and his colleagues modelled how much energy, water and carbon today's leading AI servers could use by 2030, taking into account different growth scenarios and possible data centre locations within the United States. They combined projected chip supply, server power usage and cooling efficiency with state-by-state electrical grid data to conduct their analysis. While not every AI company has set a net zero target, some larger tech firms that are active in AI, such as Google, Microsoft and Meta have set goals with a deadline of 2030. "The rapid growth of AI computing is basically reshaping everything," says You. "We're trying to understand how, as a sector grows, what's going to be the impact?"

An aerial view of an Amazon Web Services Data Center known as US East 1 in Ashburn, Virginia on 20 October 2025. An aerial view of an Amazon Web Services Data Center known as US East 1 in Ashburn, Virginia on 20 October 2025. Thu 30 Oct 2025 16.50 EDTLast modified on Fri 31 Oct 2025 05.25 EDT Amazon has made its first financial disclosures since the disastrous outage suffered by its cloud computing division that brought everything from smart beds to banks offline. In spite of the global outage, Amazon Web Services has continued to grow, and this quarter reported a 20% increase in revenue year over year. Wall Street estimated that AWS would bring in $32.42bn in net sales in the third quarter, with the company reporting actual revenue of $33bn.

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High-resolution tissue imaging is often compromised by sample-induced optical aberrations that degrade resolution and contrast. While wavefront sensor-based adaptive optics (AO) can measure these aberrations, such hardware solutions are typically complex, expensive to implement, and slow when serially mapping spatially varying aberrations across large fields of view. Here, we introduce AOViFT (Adaptive Optical Vision Fourier Transformer) -- a machine learning-based aberration sensing framework built around a 3D multistage Vision Transformer that operates on Fourier domain embeddings. AOViFT infers aberrations and restores diffraction-limited performance in puncta-labeled specimens with substantially reduced computational cost, training time, and memory footprint compared to conventional architectures or real-space networks. We validated AOViFT on live gene-edited zebrafish embryos, demonstrating its ability to correct spatially varying aberrations using either a deformable mirror or post-acquisition deconvolution. By eliminating the need for the guide star and wavefront sensing hardware and simplifying the experimental workflow, AOViFT lowers technical barriers for high-resolution volumetric microscopy across diverse biological samples.

Human mobility modeling from GPS-trajectories and synthetic trajectory generation are crucial for various applications, such as urban planning, disaster management and epidemiology. Both of these tasks often require filling gaps in a partially specified sequence of visits - a new problem that we call "controlled" synthetic trajectory generation. Existing methods for next-location prediction or synthetic trajectory generation cannot solve this problem as they lack the mechanisms needed to constrain the generated sequences of visits. Moreover, existing approaches (1) frequently treat space and time as independent factors, an assumption that fails to hold true in real-world scenarios, and (2) suffer from challenges in accuracy of temporal prediction as they fail to deal with mixed distributions and the inter-relationships of different modes with latent variables (e.g., day-of-the-week). These limitations become even more pronounced when the task involves filling gaps within sequences instead of solely predicting the next visit. We introduce TrajGPT, a transformer-based, multi-task, joint spatiotemporal generative model to address these issues. Taking inspiration from large language models, TrajGPT poses the problem of controlled trajectory generation as that of text infilling in natural language. TrajGPT integrates the spatial and temporal models in a transformer architecture through a Bayesian probability model that ensures that the gaps in a visit sequence are filled in a spatiotemporally consistent manner. Our experiments on public and private datasets demonstrate that TrajGPT not only excels in controlled synthetic visit generation but also outperforms competing models in next-location prediction tasks - Relatively, TrajGPT achieves a 26-fold improvement in temporal accuracy while retaining more than 98% of spatial accuracy on average.

Population activity measurement by calcium imaging can be combined with cellular resolution optogenetic activity perturbations to enable the mapping of neural connectivity in vivo. This requires accurate inference of perturbed and unperturbed neural activity from calcium imaging measurements, which are noisy and indirect, and can also be contaminated by photostimulation artifacts. We have developed a new fully Bayesian approach to jointly inferring spiking activity and neural connectivity from in vivo all-optical perturbation experiments. In contrast to standard approaches that perform spike inference and analysis in two separate maximum-likelihood phases, our joint model is able to propagate uncertainty in spike inference to the inference of connectivity and vice versa. We use the framework of variational autoencoders to model spiking activity using discrete latent variables, low-dimensional latent common input, and sparse spike-and-slab generalized linear coupling between neurons.